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IL-10
  • 品牌:湖南瑞威尔
  • 货号:RWE20230505
  • 发布日期: 2024-04-26
  • 更新日期: 2024-08-29
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产地
货号 RWE20230505
品牌 湖南瑞威尔
用途 外贸出口、科学研究和化学试剂等领域
英文名称
包装规格
CAS编号
别名
纯度 %
包装
分子式
级别 医药级
Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by
lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-
regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on
macrophages. It also enhances B cell survival, proliferation, and antibody production. This
cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling

pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.


Aliases IL10
Entrez GeneID 3586
Swissprot P22301
clone 3C12C12
Host/Isotype Mouse IgG1
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human IL-10 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.


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