产品展厅
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PDK1
- 品牌：湖南瑞威尔
- 货号：RWE202302105
- 发布日期： 2024-04-26
- 更新日期： 2024-08-29
产品详请
| 产地 | |
| 货号 | RWE202302105 |
| 品牌 | 湖南瑞威尔 |
| 用途 | 外贸出口、科学研究和化学试剂等领域 |
| 英文名称 | |
| 包装规格 | |
| CAS编号 | |
| 别名 | |
| 纯度 | % |
| 包装 | |
| 分子式 | |
| 级别 | 医药级 |
| Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. (provided by RefSeq). Tissue specificity: Expressed predominantly in the heart. |
| References |
|---|
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1. Nat Cell Biol. 2008 Feb;10(2):127-37. 2. Blood. 2008 Apr 1;111(7):3723-34. 3. J Biol Chem. 2007 Apr 20;282(16):12272-89. |
| Specification | |
|---|---|
| Aliases | PDK1 |
| Entrez GeneID | 5163 |
| Swissprot | Q15118 |
| clone | 4A11 |
| WB Predicted band size | 44kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Monkey,Rat |
| Immunogen | Purified recombinant fragment of human PDK1 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
