产品展厅
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BMPR2
- 品牌：湖南瑞威尔
- 货号：RWE202302105
- 发布日期： 2024-04-26
- 更新日期： 2024-08-29
产品详请
| 产地 | |
| 货号 | RWE202302105 |
| 品牌 | 湖南瑞威尔 |
| 用途 | 外贸出口、科学研究和化学试剂等领域 |
| 英文名称 | |
| 包装规格 | |
| CAS编号 | |
| 别名 | |
| 纯度 | % |
| 包装 | |
| 分子式 | |
| 级别 | 医药级 |
| This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. (provided by RefSeq) |
| References |
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1. J Heart Lung Transplant. 2008 Jun;27(6):668-74. 2. Genet Med. 2008 May;10(5):359-65. |
| Specification | |
|---|---|
| Aliases | BMR2; PPH1; BMPR3; BRK-3; T-ALK; BMPR-II; FLJ41585; FLJ76945; BMPR2 |
| Entrez GeneID | 659 |
| Swissprot | Q13873 |
| clone | 1F12 |
| WB Predicted band size | 115kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat,Monkey |
| Immunogen | Purified recombinant fragment of human BMPR2 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
