产品展厅
IRAK4
- 品牌:湖南瑞威尔
- 货号:RWE20230258
- 发布日期: 2024-04-28
- 更新日期: 2025-01-09
产品详请
产地 | |
货号 | RWE20230258 |
品牌 | 湖南瑞威尔 |
用途 | 外贸出口、科学研究和化学试剂等领域 |
英文名称 | |
包装规格 | |
CAS编号 | |
别名 | |
纯度 | % |
包装 | |
分子式 | |
级别 | 医药级 |
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
References |
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1. J Biol Chem. 2010 Jun 11;285(24):18276-82. 2. Scand J Immunol. 2009 Sep;70(3):264-76. |
Specification | |
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Aliases | IPD1; REN64; NY-REN-64 |
Entrez GeneID | 51135 |
Swissprot | Q9NWZ3 |
clone | 2H9 |
WB Predicted band size | 52kDa |
Host/Isotype | Mouse IgG1 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Monkey |
Immunogen |
Purified recombinant fragment of human IRAK4 expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |