湖南瑞威尔生物科技有限公司
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CCL2
  • 品牌:湖南瑞威尔
  • 货号:RWE20230505
  • 发布日期: 2024-04-28
  • 更新日期: 2024-08-29
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产地
货号 RWE20230505
品牌 湖南瑞威尔
用途 外贸出口、科学研究和化学试剂等领域
英文名称
包装规格
CAS编号
别名
纯度 %
包装
分子式
级别 医药级
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
References
J Cereb Blood Flow Metab. 2010 Mar;30(3):459-73.
Prostate. 2010 Mar 1;70(4):433-42.
Specification
Aliases HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
Entrez GeneID 6347
Swissprot P13500
clone 2D8
WB Predicted band size 11kDa
Host/Isotype Mouse IgG1
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Monkey
Immunogen Purified recombinant fragment of human CCL2 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
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