湖南瑞威尔生物科技有限公司
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GPC3
  • 品牌:湖南瑞威尔
  • 货号:RWE20230205
  • 发布日期: 2024-04-28
  • 更新日期: 2024-08-29
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产地
货号 RWE20230205
品牌 湖南瑞威尔
用途 外贸出口、科学研究和化学试剂等领域
英文名称
包装规格
CAS编号
别名
纯度 %
包装
分子式
级别 医药级
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
References
1. Int J Cancer. 2010 Mar 15;126(6):1291-301.
2. Cancer Biol Ther. 2009 Dec;8(24):2329-38.
Specification
Aliases SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2
Entrez GeneID 2719
Swissprot P51654
clone 9C2
WB Predicted band size 65.5kDa
Host/Isotype Mouse IgG1
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Purified recombinant fragment of human GPC3 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

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