产品展厅
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TGFb1
- 品牌：湖南瑞威尔
- 货号：RWE20230258
- 发布日期： 2024-04-28
- 更新日期： 2024-08-29
产品详请
| 产地 | |
| 货号 | RWE20230258 |
| 品牌 | 湖南瑞威尔 |
| 用途 | 外贸出口、科学研究和化学试剂等领域 |
| 英文名称 | |
| 包装规格 | |
| CAS编号 | |
| 别名 | |
| 纯度 | % |
| 包装 | |
| 分子式 | |
| 级别 | 医药级 |
| This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease |
| References |
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1.Cell. 2011 Oct 28;147(3):565-76. 2.Kobe J Med Sci. 2011 May 11;56(6):E242-52. |
| Specification | |
|---|---|
| Aliases | CED; LAP; DPD1; TGFB; TGFbeta |
| Entrez GeneID | 7040 |
| Swissprot | P01137 |
| clone | 7F6 |
| WB Predicted band size | 44.3kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen |
Purified recombinant fragment of human TGFb1 (AA: 62-195) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
