产品展厅
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C3C
- 品牌：湖南瑞威尔
- 货号：RWE20230258
- 发布日期： 2024-04-28
- 更新日期： 2024-08-29
产品详请
| 产地 | |
| 货号 | RWE20230258 |
| 品牌 | 湖南瑞威尔 |
| 用途 | 外贸出口、科学研究和化学试剂等领域 |
| 英文名称 | |
| 包装规格 | |
| CAS编号 | |
| 别名 | |
| 纯度 | % |
| 包装 | |
| 分子式 | |
| 级别 | 医药级 |
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Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. |
| References |
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1.Blood. 2015 Apr 9;125(15):2359-69. 2.Mediators Inflamm. 2013;2013:716902. |
| Specification | |
|---|---|
| Aliases | ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p |
| Entrez GeneID | 718 |
| Swissprot | P01024 |
| clone | 4C6A8 |
| WB Predicted band size | 187.1kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human C3C (AA: 1521-1649) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
